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In Kagoshima, the boy Koichi lives with his mother Nozomi in the house of his grandparents. Koichi misses his younger brother Ryunosuke and his father Kenji, who live in Fukuoka, and he dreams on his family coming together again. One day, Koichi overhears that the energy released by two bullet trains passing by each other would grant wishes and he invites his two best friends, Tasuku and Makoto, to travel to the point of intersection of the two trains. Koichi also tells his plan to Ryunosuke that invites his three best friends to join him. Soon the seven children arrive to the meeting point in the journey of discoveries.
Dr. Hattori and her husband watch footage of brain surgery experiments with Manchurian, Russian and Japanese guinea pigs that had been found in the basement of a wrecked hospital. Out of the blue, there is a white light and when they look back, they see they children Ota Miyuki and Kaori staring at the light. Years later, Miyuki vanishes from the Tama Medical University Hospital and her sister Kaori, Miyuki's boyfriend Motojima and detective Hirasawa are seeking her. However, Miyuki and the teenagers Kazochi, Takumi, Hattori and Rieko have been submitted to a nightmarish experiment by Dr. Hattori and her team with tragic results.
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